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1. Dr Anthony Fauci Interview
(Fundamental Science)
We have posted an interesting interview of Professor Anthony Fauci about HIV reservoirs research. You can find it in the News section. Thanks. Do not miss this article.  ...
Wednesday, 29 December 2010
... CD8+ T cell frequencies and cell-associated HIV burden was found. These data support a model in which HIV-specific CD4+ T cells may replenish the latent reservoir and prevent the natural eradication ...
Wednesday, 26 January 2011
... and that is the purpose of the ‘HIV Persistence During Therapy International Workshop’. This gathering of top researchers in the field of HIV reservoirs is bound to be a fruitful time, and now we find ...
Thursday, 14 April 2011
Alain Lafeuillade (France) and Mario Stevenson (USA) co-authored a paper on HIV reservoirs that claims these reservoirs are the main hurdle to achieving HIV eradication.  While antiretroviral therapy treatments ...
Friday, 27 May 2011
...  Abstract: Despite long-term viral suppression with antiretroviral therapy (ART), HIV persists in reservoirs and sanctuary sites. Lifelong therapy is therefore necessary, leading to problems of compliance, ...
Tuesday, 21 June 2011
6. Fresh Air for HIV Cure Research
(Clinical Aspects)
... be receiving just over $4 million each year. Both UCSF and VGTI will use an immune-based treatment as well as small molecules in their attempts to shrink the reservoirs of infected cells.   The National ...
Saturday, 23 July 2011
7. Tracking HIV in its Final Refuge
(Fundamental Science)
... of the dormant virus within the body in order for the body's immune system to kill it.  While the drugs currently available don't go as far as eliminating the HIV in the reservoirs within the cells, these ...
Friday, 29 July 2011
... in HIV reservoirs. HIV reservoirs are the last hiding place for HIV. These reservoirs are pockets inside the body (usually cells in the brain, gut and other organs) where HIV hides out and lies dormant, ...
Tuesday, 02 August 2011
Researchers at the California Institute of Technology (Caltech) believe they have begun to decode how a reservoir of infection can persist in HIV-positive populations. Their work is published ahead ...
Friday, 19 August 2011
Professor Mario Stevenson (Miami, USA) has some interesting news to bring to the HIV research community at large. In a recent interview conducted at the 5th International Workshop on HIV Persistence, Reservoirs ...
Wednesday, 14 December 2011
The elimination of HIV reservoirs is what is often seen as the final step in finding a cure for HIV. During antiretroviral therapy (ART), the drugs are very effective in eliminating HIV from the bloodstream; ...
Saturday, 31 December 2011
12. Can gut microbiota and systemic inflammation limit HIV vaccine effectiveness?
(News/Latest News on HIV Reservoirs & Eradication)
Can gut microbiota and systemic inflammation limit HIV vaccine effectiveness? In this elegant article, Professor Jean-Pierre Routy, asks the question of the gut microbia and systemic inflammation ...
Tuesday, 20 June 2017
13. 2017 CROI Coverage: 16 February
(News/Latest News on HIV Reservoirs & Eradication)
2017 CROI Coverage: 16 February For the last day of the 2017 Conference on Retroviruses and Opportunistic Infection (CROI) held in Seattle, Chritina Psomas, MD, PhD, from the University of Montpellier, ...
Friday, 17 February 2017
14. 2017 CROI: 15 February Coverage
(News/Latest News on HIV Reservoirs & Eradication)
... always highest in white matter, because the white matter compartment contains the most mass. The intensity of systemic viral replication does not influence HIV reservoir size in brain, PBMCs, gastrointestinal ...
Thursday, 16 February 2017
15. 2017 CROI: 14 February Coverage
(News/Latest News on HIV Reservoirs & Eradication)
... expansion. These cells are responsible for viral load rebound following ART interruption. Tissues are reservoirs for HIV and ongoing viral replication can occur to tissues because of limited ART penetration ...
Wednesday, 15 February 2017
16. 2017 CROI: 13 February Coverage
(News/Latest News on HIV Reservoirs & Eradication)
... into HIV treatment programs.   Dr Nicolas Chomont from Montreal did an outstanding presentation on mechanisms of HIV persistence in active or latent reservoirs and the potential of HIV cure. Even if ...
Tuesday, 14 February 2017
17. Daniel Kuritzkes Lecture at ISHEID
(News/Latest News on HIV Reservoirs & Eradication)
... pilot studies are underway with each of these approaches. Major challenges include the lack of surrogate markers of cure (difficulty of quantifying the HIV reservoir for instance during the monitored ART ...
Friday, 17 June 2016
18. 2016 CROI Coverage: Thursday 25
(News/Latest News on HIV Reservoirs & Eradication)
... could be used in the future to monitor reservoir cells of the brain, as well as to monitor effects of ART in the brain. Xiang Li presented his results concerning CSF lymphocyte and monocyte activation ...
Thursday, 25 February 2016
19. 2016 CROI Coverage: Wednesday 24
(News/Latest News on HIV Reservoirs & Eradication)
... with a subsequent repair disrupting this gene. Infusion of ZFN-treated ex vivo expanded T cells is generally safe and well tolerated and induces durable increase in both CD4, total T-cell counts, reservoir ...
Wednesday, 24 February 2016
20. 2016 CROI Coverage: 23 February
(News/Latest News on HIV Reservoirs & Eradication)
... can also be used as a treatment, in a complementary way to ART, in order to block viral entry, or to eliminate infected cells, having an impact on the cell-associated viral reservoir. Thus, mAbs may be ...
Wednesday, 24 February 2016
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