CNS Reservoir Satellite Meeting PDF Print E-mail
Written by Alain Lafeuillade   
Thursday, 17 November 2011 14:49

Unique Challenges and Opportunities for Eradication of CNS HIV Reservoirs

brain-hivThe Division of AIDS Research at the US National Institute of Mental Health is organizing a satellite meeting on December 6, 2011 prior to the opening of the "Fifth International Workshop on HIV Persistence during Therapy" at Westin St Maarten Dawn Beach Resort, St Maarten, West Indies.


HIV cure is a key priority area for NIH and NIAID recently awarded $14 million/year for research on eradication of HIV through the Martin Delaney Collaboratory.


A number of HIV eradication strategies are currently being developed. However for successful cure, it may be necessary to target HIV brain reservoirs. 


This meeting will examine current approaches for eradication and their impact on brain HIV reservoirs. 

Some of the approaches being developed may be detrimental for brain and CNS issues needs to be considered before initiating human trials. Unique strategies for eliminating CNS reservoirs will also be discussed. 


This meeting will convene leading HIV researchers and NeuroAIDS experts to address unique challenges and opportunities for eradication of brain HIV-1 reservoirs.



Jeymohan Joseph, PhD

Chief, HIV Pathogenesis, Neuropsychiatry and Treatment Branch

Division of AIDS Research

National Institute of Mental Health

Room 6219, MSC 9619

6001 Executive Boulevard

Bethesda, MD 20892

Telephone: 301-443-3012

Fax: 301-443-9719



3:00 – 3:05 PM

Meeting Goals

Jeymohan Joseph, NIMH, Bethesda, MD

3:05 – 3:15 PM

HIV Reservoirs and Sanctuary Sites: Overview

Alain Lafeuillade, Dept Infectious Diseases, General Hospital,  Toulon, France 

3:15 – 3:25 PM

Mechanism of HIV Persistence

Tae-Wook Chun, NIAID, NIH, Bethesda, MD, USA

3:25 – 3:35 PM 

Current Strategies for Eradication of HIV

Steven Deeks, University of California, San Francisco, CA, USA

3:35 – 3:45 PM

Astrocytes  as a significant CNS Reservoir for proviral HIV DNA

Melissa Churchill, Burnet Institute, Melbourne, Australia

3:45 – 3:55 PM

The Role of Macrophages/Microglia as a CNS reservoir

Mario Stevenson, University of Miami, Miami, FL, USA

3:55 PM – 4:05 PM

Novel Approaches for detection of low level persistent HIV in CNS

Sarah Palmer, Karolinska Institute, Stockholm, Sweden, USA

4:05 – 4:15 PM

Novel strategies for delivery of anti-retrovirals into the brain using nanoparticles

David Margolis, University of North Carolina-Chapel Hill, NC, USA

4:15 – 4:25 PM

Unique CNS Challenges for Current Eradication Strategies

Janice Clements, Johns Hopkins University, Baltimore, MD, USA

4:25 – 5:30 PM

Discussion of CNS Challenges and Targeted Approaches for HIV Eradication

Co-Chairs: Mario Stevenson, University of Miami, Miami, FL, USA

                Avindra Nath, NINDS, Bethesda, MD, USA


You can download this program by using this link:

Download the agenda

Key words: HIV cure, HIV eradication, HIV reservoirs
Last Updated on Thursday, 17 November 2011 15:13
Comments closed!